Thursday Night Football: 49ers vs. Giants

Week 3 of the 2023 NFL season will kick off with a Thursday night football matchup featuring the New York Giants on the road against the San Francisco 49ers.

These teams are tied at 17 games each in their all-time series, but the Niners have won two of the three most-recent meetings. They last faced off back in 2020, when San Francisco won easily on the road, 36-9. The Giants and Niners are also tied at 4 game a piece in the postseason, but New York beat San Francisco in the NFC Championship game in 2012.

Sure, the Giants were able to spark a great comeback last week against Jonathan Gannon and the Cardinals, but the 49ers are a whole different monster. It’ll be a tough one for the Philadelphia Eagles’ NFC East rival.

Here’s everything you need to know about tonight’s game.

New York Giants vs. San Francisco 49ers

TV Schedule

Date: Thursday, September 21, 2023

Time: 8:15 PM ET

Channel: Amazon Prime Video (nationally)

Location: Levi’s Stadium | Santa Clara, CA

Announcers: Al Michaels, Kirk Herbstreit, Kaylee Hartung

Sirius: 81 (NYG), 83 (SF), 88 (National) | XM: 226 (NYG), 225 (SF)

Online Streaming

FuboTV | Amazon Prime Video

Odds according to DraftKings Sportsbook

New York Giants: +10.5 (+360)

San Francisco 49ers: -10.5 (-470)

Over/Under: 43.5

BLG Pick: Niners -10.5

SB Nation Blogs

Giants: www.BigBlueView.com

49ers: www.NinersNation.com

Open thread: Discuss Thursday night’s game in the comments below.