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NFL Picks Against the Spread: Week 6 Games

Here are some suggestions when trying to beat the odds.

Philadelphia Eagles v Dallas Cowboys Photo by Cooper Neill/Getty Images

Before the sixth Sunday of the 2022 NFL regular season kicks off, let’s have some fun by taking a look at the spreads for the Week 6 games.

You can CLICK HERE for straight up NFL picks WITHOUT regard to the spread. You can find all of the NFL betting lines via DraftKings Sportsbook.

My overall record so far is 37-39-3. Need to get back above .500. The BGN community is slightly behind at 36-40-3.

Here are suggestions when trying to beat the odds. Also, don’t forget to check out our weekly picks and previews of every game on The SB Nation NFL Show’s The Look Ahead podcast featuring RJ Ochoa, Rob “Stats” Guerrera, and me.

NFL WEEK 6 GAMES

DALLAS COWBOYS at PHILADELPHIA EAGLES (-6.5): Say it with me: the Eagles are going to comfortably beat the Cowboys on Sunday night. I want you to actually say it out loud. Don’t just read it. This isn’t about unabashed homerism. This is about being disrespectful to Dallas, who appear to be one of the few legitimately good teams in the NFL this year. It’s about believing in an Eagles team that has looked very good much more often than not this year. Don’t fall into the trap of overreacting to the ugly win over Arizona. The Eagles’ performance last week was more anomalous than it was indicative. The Birds’ offensive line is going to neutralize the Cowboys’ pass rush. Your mileage may vary when it comes to confidence in Jonathan Gannon but he’s always been able to shut down lesser quarterbacks like Rush. Rush, by the way, is basically guaranteed to turn the ball over at least once after not doing so at all this year. It’s due to happen. All told, the Eagles simply match up well against the Cowboys. Also, the crowd is going to be absolutely bonkers given the magnitude of this game and the additional context of the Phillies going to the NLCS. This city is fired up right now. This game is my LOCK OF THE WEEK for The SB Nation NFL Show. And let the record show I am leading the standings at 4-1 when it comes to my locks. PICK: Eagles -6.5

Poll

Which bet do you like more?

This poll is closed

  • 28%
    Cowboys +6.5
    (49 votes)
  • 71%
    Eagles -6.5
    (123 votes)
172 votes total Vote Now

BALTIMORE RAVENS (-6) at NEW YORK GIANTS: The Giants look legitimately respectable for the first time in a long time. But their offense isn’t going to be able to keep up with Lamar Jackson. PICK: Ravens -6

Poll

Which bet do you like more?

This poll is closed

  • 50%
    Ravens -6
    (59 votes)
  • 50%
    Giants +6
    (59 votes)
118 votes total Vote Now

NEW YORK JETS at GREEN BAY PACKERS (-7.5): Look, I know the Packers have looked like ass. And the Jets are coming off of a big win. But I’m not about to overreact to last week. This is still Aaron Rodgers vs. Zach Wilson that we’re talking about here. And Wilson has really never looked all that good. PICK: Packers -7.5

Poll

Which bet do you like more?

This poll is closed

  • 65%
    Jets +7.5
    (71 votes)
  • 34%
    Packers -7.5
    (37 votes)
108 votes total Vote Now

TAMPA BAY BUCCANEERS (-10) at PITTSBURGH STEELERS: Pittsburgh is really banged up but betting against Mike Tomlin as an underdog is not an easy thing to do. Also, the Bucs just don’t look totally right. They’ll win the game but Kenny Pickett will find a way to cover, be it in garbage time or otherwise. PICK: Steelers +10

Poll

Which bet do you like more?

This poll is closed

  • 43%
    Buccaneers -10
    (44 votes)
  • 56%
    Steelers +10
    (57 votes)
101 votes total Vote Now

SAN FRANCISCO 49ERS (-4) at ATLANTA FALCONS: The 49ers are dealing with some significant injury issues but I trust DeMeco Ryans to make it worth. The Falcons don’t have the firepower to score on San Fran’s defense. Few teams do. PICK: 49ers -4

Poll

Which bet do you like more?

This poll is closed

  • 61%
    49ers -4
    (61 votes)
  • 38%
    Falcons +4
    (38 votes)
99 votes total Vote Now

MINNESOTA VIKINGS (-3.5) at MIAMI DOLPHINS: Kirk Cousins is capable of handling business against inferior opponents and that’s what the Dolphins are with Skylar Thompson under center. PICK: Vikings -3.5

Poll

Which bet do you like more?

This poll is closed

  • 83%
    Vikings -3.5
    (76 votes)
  • 16%
    Dolphins +3.5
    (15 votes)
91 votes total Vote Now

CINCINNATI BENGALS (-3) at NEW ORLEANS SAINTS: The Saints were buoyed by a big Taysom Hill rushing game and an inexplicable special teams gaffe last week. Not exactly the most sustainable factors. Joe Burrow and Ja’Marr Chase will show up in their return to Louisiana. PICK: Bengals -3

Poll

Which bet do you like more?

This poll is closed

  • 78%
    Bengals -3
    (67 votes)
  • 21%
    Saints +3
    (18 votes)
85 votes total Vote Now

NEW ENGLAND PATRIOTS at CLEVELAND BROWNS (-3): The Browns’ ceiling is obviously limited with Jacoby Brissett but he should be able to beat his former team. PICK: Browns -3

Poll

Which bet do you like more?

This poll is closed

  • 54%
    Patriots +3
    (42 votes)
  • 45%
    Browns -3
    (35 votes)
77 votes total Vote Now

JACKSONVILLE JAGUARS at INDIANAPOLIS COLTS (-2): Why are the Colts giving points? They had a fluky win over KC and barely beat a pretty uninspiring Denver team. The Jags have not been consistent but they’ve demonstrated the higher ceiling. Doug Pederson has never lost to Frank Reich. PICK: Jaguars +2

Poll

Which bet do you like more?

This poll is closed

  • 73%
    Jaguars +2
    (58 votes)
  • 26%
    Colts -2
    (21 votes)
79 votes total Vote Now

CAROLINA PANTHERS at LOS ANGELES RAMS (-9.5): Give me the Panthers OUTRIGHT. They have the “bad head coach was fired” bump going for them. Especially with players on notice and/or motivated to showcase their services ahead of the NFL trade deadline. Also, the Rams aren’t good! LA ranks 25th in DVOA and 31st in point differential. PICK: Panthers +9.5

Poll

Which bet do you like more?

This poll is closed

  • 49%
    Panthers +9.5
    (38 votes)
  • 50%
    Rams -9.5
    (39 votes)
77 votes total Vote Now

ARIZONA CARDINALS (-2.5) at SEATTLE SEAHAWKS: The Cards typically have success up in the Pacific Northwest. However, they still don’t have DeAndre Hopkins. And Geno Smith is straight up cooking right now. I’ll ride with the home dogs. PICK: Seahawks +2.5

Poll

Which bet do you like more?

This poll is closed

  • 48%
    Cardinals -2.5
    (36 votes)
  • 51%
    Seahawks +2.5
    (38 votes)
74 votes total Vote Now

BUFFALO BILLS (-2.5) at KANSAS CITY CHIEFS: Certainly not every day that you’re to be able to take Patrick Mahomes getting points at home. PICK: Chiefs +2.5

Poll

Which bet do you like more?

This poll is closed

  • 58%
    Bills -2.5
    (20 votes)
  • 41%
    Chiefs +2.5
    (14 votes)
34 votes total Vote Now

DENVER BRONCOS at LOS ANGELES CHARGERS (-4.5): Watching the Broncos play offense is downright painful. How could one possibly put their faith in them. PICK: Chargers -4.5

Poll

Which bet do you like more?

This poll is closed

  • 9%
    Broncos +4.5
    (7 votes)
  • 90%
    Chargers -4.5
    (65 votes)
72 votes total Vote Now

Odds/lines subject to change. T&Cs apply. See draftkings.com/sportsbook for details.

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