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Eagles might be playing a 49ers team that’s missing their starting quarterback

Injury issues on both sides.

NFL: San Francisco 49ers-Minicamp Stan Szeto-USA TODAY Sports

The Philadelphia Eagles might be facing a San Francisco 49ers team that’s missing starting quarterback Jimmy Garoppolo again this week. Jimmy G was not seen participating in Wednesday’s practice due to the ankle injury he suffered in Week 2.

The 49ers fared quite well without their primary signal caller in Week 3. Third-year backup Nick Mullens completed 69% (nice) of his attempts for 343 yards (9.5 average) for one touchdown, zero interceptions, and a 108.9 passer rating in a 27-point win over the New York Giants. The Giants are undoubtedly awful but Mullens still did this despite the fact the 49ers were missing offensive weapons like George Kittle, Deebo Samuel, Raheem Mostert, and Tevin Coleman.

The good news for the 49ers and the bad news for the Eagles is that it looks like Kittle will be back since he fully practiced on Wednesday. One can only imagine how he’s going to victimize Nathan Gerry. Samuel also has a chance to play with the 49ers opening his 21-day practice window.

And so even if Jimmy G doesn’t suit up, San Fran still figures to be a formidable challenge for the 0-2-1 Eagles. Mullens is no slouch and neither is the 49ers’ offensive coaching with Kyle Shanahan running the show.