The only somewhat surprising note is that rookie tight end Trey Burton has been ruled out. Burton is a key contributor on Philadelphia's special teams unit. The rookie from Florida was ruled questionable heading into this game due to hamstring tightness.
With Burton out, veteran wide receiver Jeff Maehl will suit up.
Starting quarterback Nick Foles is out due to a fractured collarbone. Foles' injury is expected to be re-evaluted shortly, but he could be out longer than first expected. Veteran signal caller Mark Sanchez will start in place of the injured Foles. Second-year quarterback Matt Barkley will serve as the backup to Sanchez. Veteran wide receiver Brad Smith is the team's emergency quarterback.
Andrew Gardner will start at right guard yet again in place of second-year offensive lineman Matt Tobin.
Philadelphia Eagles Inactives List:
Nick Foles - Injury.
Trey Burton - Injury.
Roc Carmichael - Depth CB.
Jaylen Watkins - Depth CB.
Julian Vandervelde - Depth OL.
Dennis Kelly - Depth OL.
Taylor Hart - Depth DE.
Seattle Seahawks Inactives List:
WR Bryan Walters, CB Jeremy Lane, LB Allen Bradford, C Max Unger, DT Travian Robertson, TE Cooper Helfet, TE RaShaun Allen.