According to a report from the NFL, Eagles star running back LeSean McCoy left the 2014 Pro Bowl game with an ankle injury. Injuries in an exhibition game like this are obviously very undesirable.
LeSean McCoy has an ankle injury. Return is doubtful #ProBowl— NFL: AroundTheLeague (@NFL_ATL) January 27, 2014
No official update has been given on the extent of McCoy's injury yet. So far, there's no reason to believe it's anything too serious. Chances are that McCoy is fine and he was being held out for precautionary reasons. Updates to come as necessary.