Bring the pressure to Eli manning. When he is under pressure he is sacked26.1 most of the time, Yea i know its not that much but that is 6 in the top 10 of Passing Under Pressure - Sack Percentage.
Make the Giants 1 dimensional. Put Nnamdi on their best receiver which is Mario Manningham if the rest of the cornerbacks do good guarding the rest of the wide receiver. That will make the Giants have to run which they are not that good at. I know the eagles aren't good at stopping the run but with Bradshaw possibly not playing they would have Brandon Jacobs and D.J. Ware. Brandon Jacobs is only averaging 3.2 yards per carry which is .2 less then what D.J. Ware has been averaging this year.
The turnover battle. If you pick Eli off early in the game there will be more picks coming because once he has 2 or 3 passes picked off theres a switch in his head called keep on throwing the picks.